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Research summary

The body’s ability to regulate energy and blood sugar—or metabolic health—doesn’t just influence women’s overall well-being, but also their reproductive health and the pace of age-related decline. To better understand these relationships, Dr. Nicole Templeman, Canada Research Chair in Metabolic Determinants of Reproduction and Aging, is examining how energy balance and nutrient-responsive hormones, such as insulin, affect reproductive aging and conditions like polycystic ovary syndrome. 

Using genetics, physiology and cell biology approaches, she and her research team are investigating how metabolic dysfunction and obesity-causing diets affect the female reproductive system and long-term health. By uncovering the mechanisms that link metabolism, reproductive function and aging, their work aims to inform personalized health strategies and preventive measures. These advances will improve reproductive health outcomes, reduce the risks of age-related diseases, and promote healthier aging for women.